Title: Quantification and characterization of mucosa-associated and intracellular Escherichia coli in inflammatory bowel disease
Authors: Elliott TR, Hudspith BN, Wu G, Cooley MB, Parkes G, Quinones B, Randall L, Mandrell RE, Fagerquist CK, Brostoff J, Rayment NB, Boussioutas A, Petrovska L, Sanderson JD
Journal: Inflamm Bowel Dis
Accepted date: 2013 Mar 13
Interpretive summary: The role of Escherichia coli (E. coli) in the pathogenicity of Crohn's disease (CD) is studied by characterizing E. coli from mucosal biopsies of CD and ulcerative colitis patients and healthy controls. The lack of characterising pathogenic features among E. coli from these different groups suggests that a defective mucosal immunity may be responsible for intracellular access of E. coli.
Publication date: 2013 Oct
Related projects: Molecular Biology of Human Pathogens Associated with Food