Title: Impact of sod on the expression of stress-related genes in Listeria monocytogenes 4b G with/without paraquat treatment
Authors: Suo Y, Liu Y, Zhou X, Huang Y, Shi C, Matthews K, Shi X
Journal: J Food Sci
Accepted date: 2014 Jun 19
Interpretive summary: The bacterium, Listeria monocytogenes, is an important food-borne pathogen that causes disease in humans and animals. L. monocytogenes is difficult to eliminate since it can form a biofilm (a complex aggregation of microorganisms growing on a solid substrate). To understand how biofilms are formed in L. monocytogenes, the gene that encodes for an enzyme known as superoxide dismutase was deleted from the bacterial genome forming what is referred to as a mutant strain. It was found that growth of the mutant strain was inhibited when exposed to environmental stresses that result in the formation of free radicals. In addition, five stress-related genes were induced in the mutant strain. Information from this study enhances the understanding of how L. monocytogenes tolerates stresses that the pathogen can encounter in foods and during food processing. This will help in the design of more effective control strategies.
Publication date: 2014 Aug 21
Related projects: Genomic and Proteomic Analysis of Foodborne Pathogens