|Title:||Managing the Emerging Risk of Trichinellosis in Organic and Free Range Pork|
|Objective:||1. Develop serological assays that differentiate swine chronically infected with zoonotic T. spiralis from swine only transiently exposed to T. murrelli. |
2. Estimate how frequently pastured pigs and feral swine are exposed to infection with enzootic and zoonotic species of trichinella.
Approach: Screen expression libraries of T. spiralis and T. murrelli with hyper-immune sera from swine to identify clones encoding species-specific diagnostic antigens. Develop antibodies that discriminate among the two types of infection. Test in experimentally infected swine. Apply to panels of serum collected from feral swine and pastured pigs. Validate against genotyped parasite specimens obtained from tissue samples matched with serum.
|Funding Source:||United States Department of Agriculture (USDA), Agricultural Research Service (ARS)|
|Institutions:||USDA/ARS - Beltsville Area Research Center|
|Project Reports:||2013 Annual Report|
2012 Annual Report
2011 Annual Report
ARS (NP 108):
Modeling effective transmission strategies and control of the world’s most successful parasite
Turner M, Lenhart S, Rosenthal BM, Sullivan A, Zhao X.
Theor Popul Biol. 2013 Jun;86:50-61.
Evidence for a population bottleneck in an Apicomplexan parasite of caribou and reindeer, Besnoitia tarandi
Madubata C, Dunams-Morel DB, Elkin B, Oksanen A, Rosenthal BM .
Infect Genet Evol. 2012 Dec;12(8):1605-13.
Eimeria that infect fish are diverse and are related to, but distinct from, those that infect terrestrial vertebrates
Molnár K, Ostoros G, Dunams-Morel D, Rosenthal BM .
Infect Genet Evol. 2012 Dec;12(8):1810-5.
Globally diverse Toxoplasma gondii isolates comprise six major clades originating from a small number of distinct ancestral lineages
Su C, Khan A, Zhou P, Majumdar D, Ajzenberg D, Dardé ML, Zhu XQ, Ajioka JW, Rosenthal BM, Dubey JP, Sibley LD .
Proc Natl Acad Sci USA. 2012 Apr 10;109(15):5844-9.
Discernible but limited introgression has occurred where Trichinella nativa and the T6 genotype occur in sympatry
Dunams-Morel DB, Reichard MV, Torretti L, Zarlenga DS, Rosenthal BM .
Infect Genet Evol. 2012 Apr;12(3):530-8.
|Food Safety Categories:||On-Farm Food Safety|
Diseases and Allergies
|Farm-to-Table categories:||On-farm food production|
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