Food Safety Research Information Office
Title:Integrated Approach to the Detection and Control of Foodborne Parasites and the Impact on Food Safety
Objective:

Objective 1: Evaluate the impact of changing management and production practices (e.g. free range, confined, organic) on the incidence of Toxoplasmosis and Trichinella in swine, as it relates to foodborne risk.

Objective 2: Assess the effectiveness of on-farm interventions (such as passive immunization therapy as a feed supplement) to prevent enteric Toxoplasma infection in swine, consequent foodborne risk, and potential interaction with Salmonella foodborne infections in swine. C.1., PS 1B, and PS 1.D, Section 4.1.

Objective 3: Evaluate the impact of anthelminthic and antiprotozoal treatments on parasitic foodborne infections in swine and the potential foodborne risk. Evaluate the impact of anthelminthic and antiprotozoal treatments on the interaction between foodborne pathogen and foodborne parasitic infections, specficially coinfections of Toxoplasma, Trichinella with Salmonaella and Campylobacter in swine, and changes following treatments. C.1., P.S., 1.A, and P.S., 1.D.

More Info:
Approach: Toxoplasma gondii infects 11-20% of the U.S. population, causing birth defects in exposed pregnant women, devastating disease in immunocompromised individuals, and illness and loss of vision in otherwise healthy adults. Consumption of infected pork may be a significant source of infection for consumers in the U.S. Meat derived from pasture-raised pigs is of particular concern, since prevalence in these pigs may exceed 50%. Reducing the risk of foodborne human infection from meat requires adherence to livestock production practices that prevent exposure of animals to the parasite at the farm level, and the development of new treatments which can be used in pasture-raised pigs to prevent infection. Trichinella spiralis is a serious zoonotic pathogen with an unusually broad host and geographic range. Trichinella species infecting game animals pose a risk to humans consuming these meat products as well as a risk to domestic pigs that feed on their carcasses. Understanding the risk to pigs that have access to infected wildlife is an important component of on-farm certification efforts. In addition, the safety of meat from pasture-raised swine needs to be assessed in light of increasing consumer demand for organically-raised meat products. We will evaluate the impact of different management and production practices (e.g. free range, confinement, organically-raised pigs) on the incidence of Toxoplasma and Trichinella in swine, as it relates to foodborne risk, and assess the effectiveness of on-farm interventions (such as passive immunization therapy as a feed supplement) to prevent enteric Toxoplasma infection in swine, consequent foodborne risk, and potential interaction with Salmonella foodborne infections in swine.
Funding Source:United States Department of Agriculture (USDA), Agricultural Research Service (ARS)
Type:Appropriated
Start Date:2010
End Date:2015
Project Number:1245-32000-090-00
Accession Number:421090
Institutions:USDA/ARS - Beltsville Area Research Center
Investigators:Dubey, Jitender
Hill, Dolores
Urban, Joseph
Zarlenga, Dante
Project Reports:2013 Annual Report
2012 Annual Report
2011 Annual Report
Published Journal
Articles USDA
ARS (NP 108):
A new atypical genotype mouse virulent strain of Toxoplasma gondii isolated from the heart of a wild caught puma (Felis concolor) from Durango, Mexico
Dubey JP, Alvarado-Esquivel C, Herrera-Valenzuela V, Gayosso-Dominguez E, Oliveira S, Verma S, Choudhary S, Kwok OC, Su C .
Vet Parasitol. 2013 Nov;197(3):674-7.
Pathogen exposure and blood chemistry in the Washington population of northern sea otters (Enhydra lutris kenyoni)
White L, Schuler K, Thomas N, Webb J, Saliki J, Ip H, Dubey JP, Frame E.
J Wildl Dis. 2013 Oct;49(4):887-99.
Isolation and genetic characterization of Toxoplasma gondii from mute swan (Cygnus olor) from the USA
Dubey JP, Choudhary S, Kwok OC, Ferreira LR, Oliveira S, Verma SK, Marks DR, Pedersen K, Mickley RM, Randall AR, Arsnoe D, Su C.
Vet Parasitol. 2013 Jul 1;195(1):42-6.
Prevalence of antibodies to Leishmania infantum and Toxoplasma gondii in horses from the north of Portugal
Lopes AP, Sousa S, Dubey J, Ribeiro AJ, Silvestre R, Cotovio M, Schallig HD, Cardoso L, Cordeiro-da-Silva A.
Parasit Vector. 2013 Jun 17;6:178.
Experimental transmission of Sarcocystis muris (Apicomplexa): Sarcocystidae from the feces of a naturally infected feral cat (Felis catus) to immunocompetent and immunocompromised mice
Kappany A, Abu-Elwafa S, Hilali M, Rosenthal B, Dunams D, Dubey JP.
J Parasitol. 2013;99(6):997-1001.
Food Safety Categories:Food and Feed Composition and Characteristics
On-Farm Food Safety
Government Policy and Regulations
Farm-to-Table Categories:On-farm food production
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